Supply Chain Manager, Planning & Capacity

Company: Amgen
Location: Holly Springs
Posted on: March 7, 2026

Job Description:

Join Amgens Mission of Serving Patients At Amgen, if you feel like youre part of something bigger, its because you are. Our shared missionto serve patients living with serious illnessesdrives all that we do. Since 1980, weve helped pioneer the world of biotech in our fight against the worlds toughest diseases. With our focus on four therapeutic areas Oncology, Inflammation, General Medicine, and Rare Disease we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, youll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, youll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. SUPPLY CHAIN MANAGER (STRATEGY & CAPACITY PLANNING) What you will do Lets do this. Lets change the world. In this role, you will be responsible for leading strategy and capacity planning activities for the ANC (Amgen North Carolina) Drug Substance manufacturing site and will report within the ANC Supply Chain team. This role will be responsible for providing internal strategic consulting and capacity expertise to help ANC reach its full potential within the Amgen network, now and in the future. This role ensures accurate, forward-looking, and standardized capacity visibility to support Master Production Scheduling (MPS), Long Range Strategy (LRS), New Product Introductions (NPI), and commercial supply reliability. The position also supports the development, maintenance, and governance of DS capacity assumptions. The role ensures alignment with network DS planning standards and requirements while enabling site leadership to make informed, data-driven decisions regarding investments, risk mitigation, and operational trade-offs. This position has visibility across site and supply chain leadership and the Global Supply Chain network. This position will be located at the Holly Springs, North Carolina manufacturing site. Support business strategy assessment of multiple production plan scenarios to determine options, resource / capital requirements, risk and mitigation strategy, financial and supply implications with support of a cross-functional stakeholder team. Develop metrics and analytics tools to rapidly assess impact of pending changes for assessment. Lead end-to-end DS capacity modeling for the ANC site; develop and maintain capacity models incorporating available days, maintenance, run rate, float, success rate, and yield assumptions. Identify manufacturing bottlenecks and quantify impact to supply and service levels. Ensure ANC DS planning assumptions align with network standards for Available Days, Run Rate, Success Rate, and Yield. Maintain accurate planning parameters within Rapid Response and SAP planning systems. Develop scenario analyses to support LRS volume expansion, NPIs, capital investments, and risk mitigation strategies. Support governance forums tied to LRS and MPS cycles Provide executive-ready summaries to support site and network decision-making. Partner cross-functionally with Manufacturing, Engineering, Process Development, and Capital Projects to validate capacity assumptions. Support ramp-up planning for new products and assets, transitioning assumptions to demonstrated performance. Monitor success rate, run rate, and yield performance against targets and support continuous improvement initiatives. Develop dashboards and visualization tools to enhance transparency and executive decision-making. Build playbook and templates to ensure documented and easy to follow processes for role successors. What we expect of you We are all different, yet we all use our unique contributions to serve patients. The Supply Chain professional we seek is a leader with these qualifications. Basic Qualifications: High school diploma / GED and 10 years of GMP Supply Chain / Manufacturing Planning experience OR Associates degree and 8 years of GMP Supply Chain / Manufacturing Planning experience OR Bachelors degree and 4 years of GMP Supply Chain / Manufacturing Planning experience OR Masters degree and 2 years of GMP Supply Chain / Manufacturing Planning experience OR Doctorate degree Preferred Qualifications: In-depth understanding of biopharmaceutical manufacturing operations Experience with regulated environments (i.e., cGMP, GDP, OSHA) Strong understanding of upstream/downstream capacity modeling and bottleneck analysis Knowledge of yield modeling, run rate, float, and success rate assumptions Experience supporting LRS and MPS Planning Cycles Strong technical and data analytic skills and proficiency with AI, Databricks, Excel, SQL, Power BI and Tableau Supply Chain, Manufacturing Planning and/or Industrial engineering educational background Experience working with planning systems such as Rapid Response and SAP Operational Excellence and continuous improvement experience in regulated industry Good knowledge of Word, Excel, Smartsheet, Miro, and ability to work easily with new software Strong analytical, problem-solving, and cross-functional collaboration skills Ability to translate complex manufacturing data into strategic insights Excellent organizational, communication, and interpersonal skills Financial and business acumen What you can expect of us As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, well support your journey every step of the way. The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications. In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include: A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan Stock-based long-term incentives Award-winning time-off plans Flexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies. Apply now and make a lasting impact with the Amgen team. careers.amgen.com In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information. Application deadline Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position. Sponsorship Sponsorship for this role is not guaranteed. As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease. Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Keywords: Amgen, Wilson , Supply Chain Manager, Planning & Capacity, Engineering , Holly Springs, North Carolina